Founder mutations in inherited cardiac diseases in the netherlands editors arthur am wilde j peter van tintelen copyright 2014 publisher bohn stafleu van loghum copyright holder bohn stafleu van loghum softcover isbn 978 90 368 0704 3 edition number 1 number of pages ix 102 topics human genetics. The 2373insg mutation in the mybpc3 gene is a founder mutation which accounts for nearly one fourth of the hcm cases in the netherlands eur heart j 2003 24 1848 53 google scholar. Founder mutations in inherited cardiac diseases in the netherlands this booklet summarizes our current knowledge of founder mutation populations extended families in the netherlands among other aspects providing insight in where these patients can be expected coloured maps of the prevalence in the 99 dutch postal code regions are provided for every phenotype. This booklet summarizes our current knowledge of founder mutation populations extended families in the netherlands among other aspects providing insight in where these patients can be expected coloured maps of the prevalence in the 99 dutch postal code regions are provided for every phenotype and what their precise phenotype is. Recurrent and founder mutations in inherited cardiac diseases in the netherlands springermedizinde skip to main content